Oxytocin

产品名称：Oxytocin ELISA
产    地：Demeditec 
产品货号：DE3117
产品规格：96 Tests
产品说明：
Special remarks:
FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
1 Description
The Oxytocin ELISA kit is a competitive immunoassay for the quantitative determination of Oxytocin in samples.
The kit uses a polyclonal antibody to Oxytocin to bind, in a competitive manner, the Oxytocin in the standard or sample or an alkaline phosphatase molecule which has Oxytocin covalently attached to it. After a simultaneous incubation at 4°C the excess reagents are washed away and substrate is added. After a short incubation time the enzyme reaction is stopped and the yellow color generated read on a microplate reader at 405 nm.
The intensity of the bound yellow color is inversely proportional to the concentration of Oxytocin in either standards or samples. The measured optical density is used to calculate the concentration of Oxytocin.
For further explanation of the principles and practice of immunoassays please see the excellent books by Chard or Tijssen.
2 Introduction
Oxytocin is a neurohypophysial peptide which is produced in the paraventricular nuclei of the hypothalamus and stored in the posterior pituitary. The molecule consists of nine amino acids linked with a [1-6] disulfide bond and a semi-flexible carboxyamidated tail. A hormone once thought to be limited to female smooth muscle reproductive physiology , more current findings have determined that oxytocin also functions as a neurotransmitter, may be involved in neuropsychiatric disorders, social/sexual behavior and is important in male reproductive physiology. Oxytocin and the related neurohypophysial peptide, Arg-Vasopressin, maintain renal water and sodium balance.
Oxytocin   H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2
Highly conserved across species boundaries, oxytocin-like neurohypophysial peptides are substituted primarily at residues 4 and/or 8. In the oxytocin-like peptide, mesotocin, a common peptide found in some fishes, reptiles, amphibians, marsupials and nonmammalian tetrapods, the leucine at residue 8 is substituted for isoleucine8. Acting in classical endocrine fashion, Oxytocin elicits regulatory effects by binding specific cell surface receptors which in turn initiate a secondary intracellular response cascade via a phosphoinositide signaling pathway.
上海玉博生物技术有限公司在为生命科学领域提供丰富的产品与信息资源方面处于国内**地位，公司提供的产品涵盖了二十多个国家近五十万种产品，而且产品的数量与信息在不断的增长和更新，公司提供的产品能够使生命科学工作者加快对生物化学，分子生物学，细胞生物学以及蛋白质组学研究的认知，以及分子诊断和临床医学领域的应用。

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!