Cortisol

产品名称：Cortisol ELISA
产    地：Demeditec 
产品货号：DE1887
产品规格：96 Tests
产品说明：
Special remarks:  Cortisol (hydrocortisone, compound F) is the main corticosteroid secreted in humans by the adrenal cortex. This steroid hormone has a molecular weight of 363.5.
In most physiological conditions, only about 10% of plasma cortisol circulates unbound from transcortin and albumin. Among the products of the human adrenal cortex, only cortisol is involved in the regulation of ACTH secretion.
As the level of free (non-protein bound) cortisol in blood rises, the release of ACTH is inhibited by the negative feedback effect. Conversely, if cortisol levels are subnormal, the negative feedback decreases, ACTH levels rise, and the adrenal cortex secretes cortisol until normal blood levels are restored.
The release of ACTH is under control of hypothalamic corticotrophin-releasing hormone (CRH); the negative feedback system involving cortisol has been identified at both hypothalamic and pituitary levels.
Normally during the day there is a fluctuation of cortisol achieving the highest level in the morning and the lowest in the night. Useful information is given when cortisol measurement is done in samples withdrawn at a fixed hour (8.00 a.m.). The main biological effects of cortisol are:  promotion of gluconeogenesis, deposition of liver glycogen, increase in blood glucose concentration when the carbohydrate utilization is reduced, effect on fat metabolism and anti-inflammatory action.
Cortisol measurement is a powerful tool for the evaluation of suspected abnormalities in glucocorticoid production: Cushing’s Syndrome (hypercortisolism), Addison’s disease or secondary adrenal insufficiency (hypocortisolism).  In many cases, it is necessary to perform dynamic tests (suppression or stimulation) in order to localize the defect at one of the three main levels (i.e. adrenal, pituitary, hypothalamus).
The above test kits measures the total (unconjugated) Cortisol in serum. There is also a method available for the measurement of free Cortisol in saliva. The metabolic activity of any steroid is just represented by the free hormone fraction which represents less than 5% of the total. The non-invasive sampling of saliva samples offers another advantage of salivary testing. Demeditec is offering such a testkit in ELISA format with the catalogue number DES6611.
上海玉博生物技术有限公司在为生命科学领域提供丰富的产品与信息资源方面处于国内**地位，公司提供的产品涵盖了二十多个国家近五十万种产品，而且产品的数量与信息在不断的增长和更新，公司提供的产品能够使生命科学工作者加快对生物化学，分子生物学，细胞生物学以及蛋白质组学研究的认知，以及分子诊断和临床医学领域的应用。

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!