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Mouse/human integrin beta-7 eFluor® 650NC (clone FIB504), **

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产品名称: Mouse/human integrin beta-7 eFluor® 650NC (clone FIB504), **
产品型号: 95-5867-42
产品展商: 原装进口
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Mouse/human integrin beta-7 eFluor® 650NC (clone FIB504), **


Mouse/human integrin beta-7 eFluor® 650NC (clone FIB504), **  的详细介绍
Mouse/human integrin beta-7 eFluor® 650NC (clone FIB504), **

产品名称:Mouse/human integrin beta-7 eFluor® 650NC (clone FIB504), 100 tests
产品货号:eBioscience 95-5867-42
产品规格:100 tests
Anti-Human/Mouse Integrin beta 7 eFluor® 650NC
Also known as: Integrin b7, Integrin beta7 ITGB7
Clone: FIB504
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 95-5867
Cat. No. Size
95-5867-41  25 tests 
95-5867-42  100 tests 
transmigration of leukocytes to extravascular spaces during the inflammatory response. The FIB504 antibody has been reported to have blocking activity.
Description: The FIB504 monoclonal antibody reacts with human and mouse integrin β7. Integrin β7 is a 130 kD glycoprotein which associates with integrin α4 (CD49d) to form the α4β7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with αE (CD103) to form the αEβ7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Main ligands for integrin α4β7 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the main ligand of integrin αEβ7 is E-cadherin (CD324). Integrin β7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response. The FIB504 antibody has been reported to have blocking activity.

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