eFluorTM 650NC anti-mouse CD8 (alpha subunit, CD8a, Ly-2) **

产品名称：eFluorTM 650NC anti-mouse CD8 (alpha subunit, CD8a, Ly-2) 100 tests
产品货号：eBioscience 95-0081-42
产品规格：100 tests
Anti-Mouse CD8a eFluor® 650NC
Also known as: CD8 alpha, Ly-2, Ly-35, Ly-B, Lyt-2
Clone: 53-6.7
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 95-0081
Cat. No. Size
95-0081-41  25 tests 
95-0081-42  100 tests 
Description: The 53-6.7 monoclonal antibody reacts with the mouse CD8a molecule. CD8a is an approximately 32-34 kDa cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha beta) or as a homodimer (CD8 alpha alpha). A majority of thymocytes and a subpopulation of mature alpha beta TCR T cells express CD8 alpha beta while gamma delta; TCR T cells, a subpopulation of intestinal intraepithelial lymphocytes (IELs) and dendritic cells express CD8 alpha alpha. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells.

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