GSK3b (Total/Phospho) InstantOne ELISA **

产品名称：GSK3b (Total/Phospho) InstantOne™ ELISA
产品货号：eBioscience 85-86173-11
产品规格：96 tests
GSK3 beta (Total/Phospho) InstantOne™ ELISA
Also known as: Glycogen synthase kinase-3 beta
RUO: For Research Use Only. Not for use in diagnostic procedures.
Attention: The Total/Phospho InstantOne ELISAs contain reagents for a total of 96 wells (24 wells total/72 wells phospho). Please contact Technical Service for a lot specific COA.
SKU# 85-86173
Cat. No. Size
85-86173-11  96 tests 
Description: The InstantOne™ ELISA is specifically engineered for accurate measurement of total and phosphorylated human and mouse GSK3b (Ser9) in cell lysates. Detection of total and phosphorylated rat GSK3b (Ser9) is also expected. The InstantOne™ ELISA kit allows for fast analysis of samples in approximately one hour. All reagents used in a traditional sandwich ELISA are added in solution to a plate followed by a wash step and detection with the TMB colorimetric substrate.
Glycogen Synthase Kinase 3 (GSK3) is a Ser/Thr kinase that exists as two isoforms, GSK3a and GSK3b. Unlike other kinases, phosphorylation at Ser9 and Ser21 for GSK3a and GSK3b, respectively, leads to inactivation of this enzyme. GSK3 has been implicated in several diseases, including cancer and diabetes, through its phosphorylation of glycogen synthase. GSK3 has also been associated with neurodegenerative diseases such as Alzheimer's disease due to its phosphorylation of the neuronal Tau protein.

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