c-Jun (Total/Phospho) InstantOne ELISA **

产品名称：c-Jun (Total/Phospho) InstantOne™ ELISA
产品货号：eBioscience 85-86163-11
产品规格：96 tests
c-Jun (Total/Phospho) InstantOne™ ELISA
Also known as: Transcription factor AP-1
RUO: For Research Use Only. Not for use in diagnostic procedures.
Attention: The Total/Phospho InstantOne ELISAs contain reagents for a total of 96 wells (24 wells total/72 wells phospho). Please contact Technical Service for a lot specific COA.
SKU# 85-86163
Cat. No. Size
85-86163-11  96 tests 
Description: The InstantOne™ ELISA is specifically engineered for accurate measurement of total and phosphorylated human and mouse c-Jun (Ser73) in cell lysates. Detection of rat c-Jun is also expected. The InstantOne™ ELISA kit allows for fast analysis of samples in approximately one hour. All reagents used in a traditional sandwich ELISA are added in solution to a plate followed by a wash step and detection with the TMB colorimetric substrate.
Jun is a member of the Activator Protein-1 (AP-1) family of transcription factors. AP-1 proteins can form homodimers (e.g., Jun/Jun) or heterodimers with other family members (e.g., Jun/Fos). AP-1 activity is highly regulated in normal cells by phosphorylation in response to growth factors, cytokines, and various other intra- and extracellular signals. Jun is phosphorylated at Ser63 and Ser73 by JNK, resulting in the ability of Jun/Jun or Jun/Fos dimers to bind DNA and modulate transcription.

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