Affinity Purified anti-mouse/human FOXJ1 (HFH-4, HFH4) 100 ug **

产品名称：Affinity Purified anti-mouse/human FOXJ1 (HFH-4, HFH4) 100 ug
产品货号：eBioscience 14-9965-82
产品规格：100 ug
Anti-Human/Mouse FOXJ1 Purified
Also known as: HFH-4, HFH4, Fox J1
Clone: 2A5
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-9965
Cat. No. Size
14-9965-80  25 ug 
14-9965-82  100 ug 
Description: This 2A5 monoclonal antibody reacts with Foxj1, a 50-kDa member of the Forkhead-box (FOX) family of winged-helix transcription factors. Expression of Foxj1 is high in ciliated epithelial cells and low in naïve T and B cells, where cellular activation results in downregulation of the factor. Foxj1 modulates germinal center formation and Th1 activation by repressing NFκB through IκBβ induction. As such, this transcription factor has been suggested to antagonize autoimmune reactions such as systemic lupus erythematosus and rheumatoid arthritis. In addition, Foxj1 has been linked to the formation of motile cilia in epithelial cells.

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