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Purified anti-human IRF-3 (interferon regulatory factor 3) **

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产品名称: Purified anti-human IRF-3 (interferon regulatory factor 3) **
产品型号: 14-9947-82
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Purified anti-human IRF-3 (interferon regulatory factor 3) **


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Purified anti-human IRF-3 (interferon regulatory factor 3) **

产品名称:Purified anti-human IRF-3 (interferon regulatory factor 3) 100 ug
产品货号:eBioscience 14-9947-82
产品规格:100 ug
Anti-Human IRF3 Purified
Also known as: IRF 3, interferon regulatory factor-3
Clone: SL-12 (SL12)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-9947
Cat. No. Size
14-9947-80  25 ug 
14-9947-82  100 ug 
Description: This SL-12 monoclonal antibody reacts with human Interferon Regulatory Factor (IRF)-3. IRF-3 is a 427 amino acid constitutively expressed member of the IRF transcription factor family that plays a critical role in the induction of type I interferons. Inactive IRF-3 continuously transits between the cytoplasm and nucleus. Virus or dsRNA induces the C-terminal phosphorylation of IRF-3 by IKKε and TBK-1. This phosphorylation results in retention of IRF-3 in the nucleus and subsequent transcription of IFN-ß, several interferon stimulated genes (ISGs), and other antiviral response genes.

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