Recombinant Rat IL-17A (Interleukin-17A, CTLA-8)**

产品名称：Recombinant Rat IL-17A (Interleukin-17A, CTLA-8) 25 ug
产品货号：eBioscience 14-8170-80
产品规格：25 ug
Rat IL-17A Recombinant Protein
Also known as: Interleukin-17A, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8, IL17
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-8170
Cat. No. Size
14-8170-62  5 ug 
14-8170-80  25 ug 
Description: Interleukin-17A (IL-17A, also known as CTLA-8 and IL-17) is a member of the IL-17 family of proinflammatory cytokines. It is most similar to IL-17F, another member of the family with which it shares 50% sequence homology. Both cytokines exist as homodimers and individual subunits from each protein can also associate into a heterodimer known as IL-17AF.
Expression of IL-17A is most often associated with the Th17 subset of CD4+ T cells, but has also been observed in CD8+ T cells, γδ T cells, and neutrophils. IL-17A is important as a neutrophil activator, and it induces inflammatory cytokine production in epithelial cells, endothelial cells, and fibroblasts through NF-κB signaling. IL-17A and Th17 cells have been implicated in various autoimmune disorders.

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