Recombinant Mouse IL-13 **

产品名称：Recombinant Mouse IL-13 25 ug
产品货号：eBioscience 14-8131-80
产品规格：25 ug
Mouse IL-13 Recombinant Protein
Also known as: Interleukin-13, IL13
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-8131
Cat. No. Size
14-8131-62  5 ug 
14-8131-80  25 ug 
Description: Mouse interleukin-13 (IL-13), originally designated p600, is a 11.6 kDa protein secreted by activated T helper cells, CD8+ T cells, and NK cells. IL-13 was originally identified in 1989 through differential hybridization of cDNA libraries prepared from T helper 1 and T helper 2 cells. IL-13 contains four cysteine residues, which form two intramolecular disulfide bonds. IL-13 shares many activities with IL-4; this relates to a requirement for IL-4Rα chain for signal transduction. The biological activities of IL-13 include suppression of macrophage cytotoxic activity, upregulation of IL-1RA expression, and suppression of inflammatory cytokine expression. IL-13 induces CD23 expression on B cells and enhances CD72, and expression of class II MHC gene products. Mouse IL-13 does not display the activities on T cells and B cell stimulatory effects which IL-4 exhibits. Mouse IL-13 is active on human and mouse cells.

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