Anti-Mouse IL-12 p35 Purified (C18.2) **

产品名称：Anti-Mouse IL-12 p35 Purified (C18.2) 500 ug
产品货号：eBioscience 14-7122-85
产品规格：500 ug
Anti-Mouse IL-12 p35 Purified
Also known as: Interleukin-12
Clone: C18.2
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-7122
Cat. No. Size
14-7122-81  50 ug 
14-7122-85  500 ug 
Description: The C18.2 antibody reacts with the p35 subunit of mouse interleukin-12 (IL-12). The C18.2 antibody is a non-neutralizing antibody. Interleukin-12 (IL-12) is a heterodimeric 70 kD (p70) cytokine composed of two covalently linked, glycosylated chains, 40kD (p40) and 35-kD (p35). IL-12 is mainly produced by monocytes, macrophages, and dendritic cells in response to bacterial products such as lipopolysaccharides (LPS), to intracellular pathogens or upon interaction with activated T cells. IL-12 was originally discovered because of its ability to induce interferon-gamma (IFN-g) production, cell proliferation, and cytotoxicity mediated by natural killer cells and T cells. It is now established that IL-12 also plays a key role in the development of Th1 responses, leading to IFN-g and IL-2 production. These cytokines can in turn promote T-cell responses and macrophage activation.

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