anti-human/mouse/rat Caspase-12 Purified Polyclonal

产品名称：anti-human/mouse/rat Caspase-12 Purified Polyclonal 50 ug
产品货号：eBioscience 14-6207-81
产品规格：50 ug
Anti-Caspase 12 Purified
Also known as: Caspase12
Clone: Polyclonal
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-6207
Cat. No. Size
14-6207-63  10 ug 
14-6207-81  50 ug 
Description: The polyclonal antibody reacts with human, mouse, and rat caspase-12. The antibody was raised against residues 100-116 of mouse Caspase-12 and reacts with human, mouse and rat Caspase-12. Caspase-12 is ubiquitously expressed in tissues and localized to the endoplasmic reticulum (ER) and activated by ER stress resulting in apoptosis. Similar to other members of the Caspase family, Caspase-12 requires cleavage of the prodomain to activate its proapoptotic form. ER stress, including disruption of ER calcium homeostasis and accumulation of excess proteins in ER, but not by membrane- or mitochondrial-targeted apoptotic signals, is responsible for Caspase-12 activation.

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