Chloramphenicol,氯霉素

Synonym:

Chloromycetin^®, D-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-4-nitrophenethyl]acetamide, D-(−)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide, D-(−)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol

CAS Number:

56-75-7

Linear Formula:

Cl₂CHCONHCH(CH₂OH)CH(OH)C₆H₄NO₂

Molecular Weight:

323.13

Beilstein Registry Number:

2225532

EC Number:

200-287-4

MDL number:

MFCD00078159

PubChem Substance ID:

24892250

Biochem/physiol Actions

Mode of Action: Inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step (elongation inhibition). Bacteriostatic.
Mode of Resistance: Acetylation by chloramphenicol acetyltransferase (cat gene).

Legal Information

Chloromycetin is a registered trademark of Parke-Davis & Co.

assay

≥98% (TLC)

mp

148-150 °C(lit.)

Gene Information

human ... CYP1A2(1544)

Personal Protective Equipment

Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

Hazard Codes

T

Risk Statements

45

Safety Statements

53-45

WGK Germany

3

RTECS

AB6825000

品名

产地

货号

规格

单价

备注

氯霉素  Chloramphenicol

Sigma

C0378

5g

询价

现货